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Functions of neutrophils
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Functions of neutrophils

Phagocytosis. Neutrophils are important elements of non-specific protection of an organism. They are the first to come to infection source or damage spot. Neutrophils neutralize not self agents with the help of their enzymes. Neutrophils can die there. Dead neutrophils form pus.

For the characteristic of phagocytic activity of neutrophils the following indexes are used:

The percent of cells which work as phagocytes (normally – 68,5 - 99,3%).

Phagocytic index (the number of agents, which 1 cell can consume, normally – 12 - 23);

Secretion of germicide substances (lysosomal cationic proteins, histones, lactoferin).

Antiviral activity (production of interferon).

Stimulation of tissue regeneration after damage (synthesis of acid glycosaminoglycans).

Participate in specific immunity by affecting the activity of T- and B-lymphocytes, increasing the amount of antibodies.

Secretion of substances that dilate blood vessels.

Sexualization of the blood. Most of neutrophils of women have satellites of nucleus that are surrounding the nucleus. One of X-chromosome is located there. That is why they are called sex chromatin (Bar’s bodies). Presence or absence of these satellites allows defining possible sexualization of the blood.



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